Publications by authors named "N Widodo"

Aim: To evaluate the essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins through CD55 and CD59 on erythrocyte (TER-119).

Methods: Streptozotocin (145 mg/kg) was used to induce diabetes mice. In diabetes mellitus (DM) model mice were treated with MA formulation for 14 days at a D1 - 500 mg/kg (M) + 620 mg/kg BW (A), D2 - 1000 mg/kg (M) + 420 mg/kg (A), and D3 - 1500 mg/kg (M) + 200 mg/kg (A).

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Objective: This study will identify specific epitopes from the 47kDa protein as the basis for making polyclonal antibodies to increasing sensitivity and specificity of 47kDa protein as bladder cancer biomarkers.

Method: The 47kDa protein epitope prediction was carried out using the in-silico method. The epitope with the highest and the lowest value was immunized to the mice for four weeks and was harvested at the fifth weeks.

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Underground Coal Gasification (UCG) requires monitoring of the gasification area because the gasification process is invisible and the reaction temperature exceeds 1000 °C. Many fracturing events that occurred due to coal heating can be captured with Acoustic Emission (AE) monitoring technique during UCG. However, the temperature conditions to generate fracturing events during UCG have not yet been clarified.

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Background: The molecular mechanism of pulsed radiofrequency (PRF) in chronic pain management is not fully understood. Chronic pain involves the activation of specific N-Methyl D-Aspartate receptors (NMDAR) to induce central sensitization. This study aims to determine the effect of PRF on central sensitization biomarker phosphorylated extracellular signal-regulated kinase (pERK), Ca influx, cytosolic ATP level, and mitochondrial membrane potential (Δψm) of the sensitized dorsal root ganglion (DRG) neuron following NMDAR activation.

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Article Synopsis
  • - The study investigates the fatalities of Indonesian healthcare workers (HCWs) due to COVID-19 from March 2020 to July 2021, revealing at least 1,545 deaths among HCWs, primarily affecting physicians, nurses, and midwives.
  • - The mortality rate for HCWs was significantly higher compared to the general population, with a rate of 1.707 deaths per 1,000 HCWs and a risk ratio of 4.92, suggesting HCWs faced nearly five times the mortality risk.
  • - The majority of deceased HCWs were aged 40 to 59, with a median age of 50, and many had pre-existing health conditions; the report highlights the urgent need for systematic
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