A case of monosomy 21.

A new case of monosomy 21 was observed in a newborn male. Characteristic clinical features include: an antimongoloid eye slants, large and low set ears, flat nose bridge, hypoplastic nipples, cardiac anomalies, muscular hypotonia, retarded psychomotor development. The karyotypes of the parents were normal.

Diagnostic significance of alpha-fetoproteins in neonatal hyperbilirubinaemias and primary cancer of the liver in adults.

The presence in the serum of alpha-1-fetoprotein (AFP) was studied by the following immunological methods: immunoprecipitation electrophoresis after Pesendorfer et al., modified micro Ouchterlony technique as described by Prince, and for quantitative determination of this fraction commercial Partigen plates with sensitivity above 1 mg/100 ml. were used (Behringwerke A.