Publications by authors named "N Vijaya Ganesh"
Here, we introduce 'TICIT', targeted integration by CRISPR-Cas9 and integrase technologies, which utilizes the site-specific DNA recombinase - phiC31 integrase - to insert large DNA fragments into CRISPR-Cas9 target loci. This technique, which relies on first knocking in a 39-basepair phiC31 landing site via CRISPR-Cas9, enables researchers to repeatedly perform site-specific transgenesis at the exact genomic location with high precision and efficiency. We applied this approach to devise a method for the instantaneous determination of a zebrafish's genotype simply by examining its color.
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- - The National Immunization Survey-Child (NIS-Child) tracks vaccination rates for U.S. children aged 19-35 months to help local authorities plan and address low coverage areas.
- - The study uses data from 2008-2018 to create county-level vaccination estimates, specifically for children born between 2007-2011 and 2012-2016, improving upon existing national data.
- - It employs advanced statistical methods to combine direct vaccination estimates with demographic and health predictors, highlighting barriers to vaccination in small areas.
The global rise in heart disease necessitates precise prediction tools to assess individual risk levels. This paper introduces a novel Multi-Objective Artificial Bee Colony Optimized Hybrid Deep Belief Network and XGBoost (HDBN-XG) algorithm, enhancing coronary heart disease prediction accuracy. Key physiological data, including Electrocardiogram (ECG) readings and blood volume measurements, are analyzed.
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