Publications by authors named "N Vick"
Survival for glioblastoma (GBM) patients with an unmethyated MGMT promoter in their tumor is generally worse than methylated MGMT tumors, as temozolomide (TMZ) response is limited. How to better treat patients with unmethylated MGMT is unknown. We performed a trial combining erlotinib and bevacizumab in unmethylated GBM patients after completion of radiation (RT) and TMZ.
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- The study explored the relationship between clinical and nonclinical factors and quality of life (QoL) in brain cancer patients, as little research has focused on this area.
- Participants included 26 patients aged 18-75 with stable brain cancer, who completed surveys on QoL and other variables; results indicated that younger age, having underage children, and living alone negatively impacted QoL.
- Findings suggest that nonclinical factors are more significantly associated with QoL than clinical factors, highlighting the need for further research to improve care for brain cancer patients.
Background: Asymptomatic solitary meningiomas are typically managed with clinical and radiographic follow-up. Multiple meningiomas represents a clinical entity distinct from solitary meningiomas and can be sporadic, radiation-induced, associated with neurofibromatosis, or exhibit other familial inheritance. The growth rate for multiple meningiomas is not known and therefore management of these complicated patients can be difficult.
View Article and Find Full Text PDFBackground: While certain inherited syndromes (e.g. Neurofibromatosis or Li-Fraumeni) are associated with an increased risk of glioma, most familial gliomas are non-syndromic.
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