MODERN EPIDEMIOLOGICAL ASPECTS OF THE PROBLEM OF UROGENITAL MYCOPLASMIS AMONG THE FEMALE POPULATION OF UKRAINE.

Objective: The aim: To study and analyze the dynamics, age, and regional characteristics of the incidence of urogenital mycoplasmosis in Ukraine during 2014-2019 and to substantiate medical and organizational approaches to improving the prevention of urogenital mycoplasmosis among women.

Patients And Methods: Materials and methods: To study the dynamics, age, and regional characteristics of the prevalence and incidence of urogenital mycoplasmosis in women, reference and statistical materials of the State Statistics Service of Ukraine, reference materials and data from reporting forms No. 9, 34, 35 of the Center for Medical Statistics for 2014-2019 were used.

PREDICTING OF RISKS OF GROUNDWATER AND SURFACE WATER POLLUTION WITH DIFFERENT CLASSES OF HERBICIDES IN SOIL IN EASTERN EUROPE CLIMATE CONDITIONS.

Application of pesticides in modern agriculture is a powerful permanent risk factor for public health and the natural environment. The aim of the study was a comparative hygienic assessment of the danger of contamination of ground and surface water sources with most widely used herbicides of different chemical classes (sulfonylureas, imidazolinones, pirimidinilkarboksilovye compounds semicarbazones). Field hygienic experiments for studying of the residues dynamics of studied herbicides concentration in agrocenosis objects were made by us in different types of soils: chernozem, sod-podzolic, podzolized forest.

[A study of IL-1Β and IDO gene polymorphisms in patients with schizophrenia].

Objective: Neurotoxic metabolites of the kynurenine pathway are thought to be implicated in the pathogenesis of schizophrenia. The enzyme indoleamine 2,3-dioxygenase (IDO) catalyzes the initial step of the kynurenine pathway that converts tryptophan to kynurenine metabolites. IDO is induced by proinflammatory cytokines.

[SNAP-25 and DTNBP1 as candidate genes for cognitive reserve in schizophrenia].

Cognitive reserve (CR) postulates that individual differences in the cognitive processes or neural networks underlying task performance allow some people to cope better than others with brain damage. An aim of the study was to search for candidate genes for CR in schizophrenia. We propose that higher frequencies of low risk alleles is observed in healthy relatives of schizophrenic patients compared to patients and controls and in patients without neurocognitive deficit and with less severity of the disease compared to other patients and controls.