. Effective empathic communication between health care providers and patients is an essential part of health care. In resource-poor contexts, evidence is needed to understand the quality and content of health care communication within real-life clinical engagements.
View Article and Find Full Text PDFTwo new genera, 17 new species, two epitypes, and six interesting new host and / or geographical records are introduced in this study. New genera include: (based on ) and (based on ). New species include: (from hypersaline sea water, Qatar), (from mycangia of , USA), (on leaves of , Brazil), (from pre-stored , South Africa), (from soil, South Africa), (from dead capsule of , Germany), (from house dust, Canada), (from soil, South Africa), (on ascomata of ascomycete on twigs of , South Africa), (on leaf litter, Spain), (on larva, Thailand), (from soil, South Africa), (from pasture mulch, South Africa), (from soil, South Africa), (on stem, bark of living tree of sp.
View Article and Find Full Text PDFBackground: Mental health conditions such as depression, anxiety and post-traumatic stress disorder (PTSD) are being increasingly recognised as common adverse outcomes for critical illness survivors. These conditions can have lasting consequences on their wellbeing, ability to return to their pre-illness level of functioning and health-related quality of life. There is a paucity of South African data in terms of the psychological aspects of the post-intensive care unit (ICU) syndrome.
View Article and Find Full Text PDFThe pace at which Next Generation Sequence data is being produced continues to accelerate as technology improves. As a result, such data are increasingly becoming accessible to biologists outside of the field of bioinformatics. In contrast, access to training in the methods of genome assembly and annotation are not growing at a similar rate.
View Article and Find Full Text PDFIn a pilot study, eleven pyrrolopyridine and pyrrolopyrimidine derivatives (specifically, 7-azaindole and 7-deazapurine derivatives) were synthesised by Suzuki cross-coupling reactions and evaluated via radioligand binding assays as potential adenosine receptor (AR) antagonists in order to further investigate the structure-activity relationships of these compounds. 6-Chloro-4-phenyl-1H-pyrrolo[2,3-b]pyridine, with a 7-azaindole scaffold, was identified as a selective A AR antagonist with a rAK value of 0.16 µM, and interestingly, the addition of a N-atom to the aforementioned fused heterocyclic ring system, creating corresponding 7-deazapurines, led to a dual A/A AR ligand (2-chloro-4-phenyl-7H-pyrrolo[2,3-d]pyrimidine: rAK: 0.
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