Publications by authors named "N V Zagidullin"
Article Synopsis
- A study of 4,882 patients explored the long-term cardiovascular outcomes of COVID-19 in relation to sex and variant type (Alpha, Delta, Omicron), revealing specific trends over an 18-month follow-up.
- Results showed that men had significantly higher cardiovascular mortality rates compared to women during the Delta wave, while no significant differences were observed during the Alpha and Omicron variants.
- The study highlights discrepancies in cardiovascular outcomes and demographic factors between the different COVID-19 variants, indicating a need for more focused research on long-term effects based on sex and variant type.
Background: COVID-19 limitations have hindered the implementation of new technologies by preventing proctors from coming to the site. We share our first experience of magnetic resonance imaging (MRI)-guided focused ultrasound (MRgFUS) treatment with an international remote online proctorship, and develop and evaluate the methodology of remote MRgFUS proctorship.
Methods: This single-center, nonrandomized controlled prospective study included 94 patients: 27 with essential tremor (ET) and 67 with tremor-dominant Parkinson's disease (PD).
Unlabelled: With the onset of the coronavirus pandemic, it has become clear that patients with diabetes are at risk for more severe and fatal COVID-19. Type 2 diabetes mellitus (T2D) is a major risk factor for adverse COVID-19 outcomes. The goal of study was to assess the characteristics and outcomes of hospitalized patients with COVID-19 with or without T2D in the hospital and at 10-month follow-up (FU).
View Article and Find Full Text PDFRole of PI3K/AKT/mTOR signaling pathway and sirtuin genes in chronic obstructive pulmonary disease development.
Vavilovskii Zhurnal Genet Selektsii
September 2023
Chronic obstructive pulmonary disease (COPD) is a multifactorial disease of the respiratory system which develops as a result of a complex interaction of genetic and environmental factors closely related to lifestyle. We aimed to assess the combined effect of the PI3K/AKT/mTOR signaling pathway (PIK3R1, AKT1, MTOR, PTEN) and sirtuin (SIRT1, SIRT3, SIRT6) genes to COPD risk. SNPs of SIRT1 (rs3758391, rs3818292), SIRT3 (rs3782116, rs536715), SIRT6 (rs107251), AKT1 (rs2494732), PIK3R1 (rs10515070, rs831125, rs3730089), MTOR (rs2295080, rs2536), PTEN (rs701848, rs2735343) genes were genotyped by real-time polymerase chain reaction (PCR) among 1245 case and control samples.
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