[Monoclonal antibodies to neuron-specific enolase in phenotyping lung cancer].

Morphological assessment of two samples of monoclonal antibodies (mcAB) to gamma-unit of neurospecific human enolase (NSE) is performed. It is established that mcABs interact in the tissue sections with neurons of the brain and spinal cord, gangliocytes of the central and peripheral nervous system this proving their specificity. 56 cases of lung carcinoma are studied using these mcABs; endocrine carcinoma was found in 11 cases, nonendocrine--in 45 cases.

[Development of endometrial cancer in one half of a double uterus].

Two observations (patients of 52- and 48-years old) in which endometrial carcinoma developed in one half of a double uterus. Tumours were highly differentiated and completely replaced a left half of the uterus. The endometrium of the right half was with no change.

[Malignant nonepithelial tumors of the lung].

The main peculiarities of the clinical course of lung sarcoma were determined from representative material of 134 patients. The main features differentiating malignant nonepithelial tumors from carcinoma of the lung are: younger age (average age 45.5 years), predominantly peripheral clinico-anatomical form (82.

[Tissue specificity of monoclonal antibodies to cells of human pulmonary adenocarcinoma].

Immunohistological localization of antigens revealed by 5 MoAbs to human lung adenocarcinoma cell line was studied by indirect immunoperoxidase technique. One of the MoAbs--A2F4--showed a relative specificity to epithelial tissues having a glandular differentiation. Except approximately 50% of normal cells of lungs and those of pulmonary tumours (mostly adenocarcinomas) they reacted with some other normal (stomach, oesophagus, breast) and tumoral (gastric, mammary and colonic) tissue cells.