STRUCTURAL AND FUNCTIONAL BONE FEATURES IN CHILDREN RESIDING IN THE RADIOLOGICALLY CONTAMINATED TERRITORIES OF UKRAINE.

Objective: Evaluation of structural features and metabolic/biochemical abnormalities of the bone tissue and relevant regulation patterns in children, residing in the radiologically contaminated territories (RCT).

Materials And Methods: Children (n = 148) aged 7 to 18 years old were involved in the study. Bone mineral density (BMD) is given in 3 grades according to the mean square deviation values, namely Grade I - standard (n = 75),Grade II - reduced (n = 45) and Grade III - very low one (n = 28).

Major chromosome rearrangements in intergeneric wheat × rye hybrids in compatible and incompatible crosses detected by GBS read coverage analysis.

The presence of incompatibility alleles in primary amphidiploids constitutes a reproductive barrier in newly synthesized wheat-rye hybrids. To overcome this barrier, the genome stabilization process includes large-scale chromosome rearrangements. In incompatible crosses resulting in fertile amphidiploids, the elimination of one of the incompatible alleles Eml-A1 or Eml-R1b can occur already in the somatic tissue of the wheat × rye hybrid embryo.

Molecular Analysis of Dihydropteroate Synthase Gene Mutations in Isolates among Bulgarian Patients with Pneumonia.

pneumonia (PCP) is a significant cause of morbidity and mortality in immunocompromised people. The widespread use of trimethoprim-sulfamethoxazole (TMP-SMZ) for the treatment and prophylaxis of opportunistic infections (including PCP) has led to an increased selection of TMP-SMZ-resistant microorganisms. Sulfa/sulfone resistance has been demonstrated to result from specific point mutations in the gene.

Study on the Prevalence of as a Causative Agent of Lung Pathology in People with Different Immune Status.

Background: pneumonia (PCP) commonly affects immunocompromised individuals, whereas in immunocompetent persons, it occurs relatively rarely, and in most cases, the infection is detected as an asymptomatic colonization. The present study aimed to establish the prevalence of infection in human hosts with different immune status (immunocompromised and immunocompetent), using molecular diagnostic methods, and to compare their diagnostic value with that of classical staining methods.

Methods: We used the collected-to-this-moment data from a prospective study on the prevalence of pneumocystosis among the Bulgarian population.

WAYS OF IMPROVING THE QUALITY OF PROSTHETICS OF MILITARY PERSONNEL.

Objective: The aim: Justify the choice of the construction material of dental prostheses, taking into account the clinical picture and concomitant diseases in military personnel and the study of the dynamics of military personnel seeking orthopedic dental care.

Patients And Methods: Materials and methods: 185 military personnel were examined and fitted with prosthetics in the period from March 2022 to March 2023. Methods: general clinical, content analysis, bibliosemantic, medical and statistical.