Resolution of a nonionic surfactant oligomeric mixture by means of DOSY with inverse micelle assistance.

DOSY is a recognized, efficient technique in the analysis of mixtures. It relies on the differences in self-diffusion coefficients, which are determined by the molecular size. Nowadays, efforts are directed towards devising matrices able to interact with the components of the mixture with differential affinity, and therefore capable to interfere with the diffusion processes and to display resolving power towards species of close, or even equal molecular weight, like isomers.

Evolution of the nonionic inverse microemulsion-acid-TEOS system during the synthesis of nanosized silica via the sol-gel process.

The cyclohexane-igepal inverse microemulsion, comprehensively established for the synthesis of silica nanoparticles in an ammonia-catalyzed sol-gel process, was alternatively studied with an acid-catalyzed sol-gel process. Tetraethyl orthosilicate (TEOS) was used as the silica precursor, while two different aqueous phases containing either HNO(3) or HCl at two different concentrations, 0.1 and 0.

Endo- and exo-inulinases: enzyme-substrate interaction and rational immobilization.

Three-dimensional models of exoinulinase from Bacillus stearothermophilus and endoinulinase from Aspergillus niger were built up by means of homology modeling. The crystal structure of exoinulinase from Aspergillus awamori was used as a template, which is the sole structure of inulinase resolved so far. Docking and molecular dynamics simulations were performed to investigate the differences between the two inulinases in terms of substrate selectivity.

Inverse nonionic microemulsion studied by means of 1H, 13C, and PGSTE NMR during silica nanoparticle synthesis.

The soluble species present in the reaction mixture that leads to silica nanoparticle production through the base catalyzed hydrolysis of tetraethyl orthosilicate (TEOS) and the successive condensation were investigated in situ, under the actual synthesis conditions, by means of 1H, 13C, and 29Si NMR spectroscopy. The two former nuclei, owing to higher sensitivity and their presence both in the reacting species and in the constituents of the W/O microemulsion (cyclohexane-igepal-CA-520-concentrated ammonia solution) afforded insight into the inverse microemulsion and allowed us to assess the kinetic rate of the hydrolysis step. It was verified that the microemulsion microstructure is maintained during the reaction.

[Clinical use of catomas and biotrit in a combined treatment of patients with chronic neurodermatitis].

In 170 patients with neurodermatitis, therapeutic benefit was studied of two new antioxidant drug preparations catomas (containing beta-carotene and tocopheroli acetas) and biotrit (extractum from the sprouting wheat). Catomas was used in applications to the area of affection with the aid of phonophoresis, biotrit in injections. It has been shown by the studies made that employment of the above drugs combined with sedatives, desensitizing and anti-inflammatory means of remediation enhances efficiency of the treatments administered, which fact was evidenced by the reduction of the mean duration of the treatment undergone by 4.