[Lamellar Inclusion Bodies in the Retinal Pigment Epithelium of Diurnal Rodents].

The ultrastructure of the retinal pigment epithelium of a diurnal rodent (Brandt's vole) was described taking into account 1) the functions of the pigment epithelium as a participant in the renewal of photoreceptor outer segment and. 2) digestion of outer segment membranes into phagosomes of the retinal pigment epithelium. The myeloid bodies were observed after exposure of the pigment epithelium to light (200 lux, 4 hours) and darkness (0,1 lux, 1,5-hour).

[PLASTIC REORGANIZATION OF THE ULTRASTRUCTURE OF SYNAPSES IN THE CEREBELLUM DUE TO TOXIC EFFECTS OF GLUTAMATE AND NO-GENERATING COMPOUND].

Ultrastructural changes in synapses between parallel fibers (PF) and the spines of Purkinje cell dendrites (PCD) in frog cerebellum were studied after exposure to high concentrations (1 mM) of glutamate (Glu) and NO-generating compound in experimental model. It was shown that exposure to Glu resulted in the envelopment of the terminal bouton by the spine, while under the influence of NO-generating compound, on the contrary, the spine was surrounded by the bouton. Morphological study has shown that in Glu solution there was the predominance of synapses in which the glial cells surrounded the spines, while in the presence of NO they covered the boutons.

Biogenesis of multilamellar membrane incorporations (myeloid bodies) in the Eolagurus luteus pigmented epithelium.

The study detected common ultrastructure of pigmented epithelium cells of Eolagurus luteus and other mammals and described its features characteristic of this species. Stages of interactions between the pigmented epithelium cells and external segments of retinal rod cells were studied. Migration of the external segments to the apical zone of a pigmented epithelium cell was observed.

Effect of locomotor activity on ultrastructure of cerebellar neurons, neurological disturbances, and survival of Krushinsky-Molodkina rats with hemorrhagic stroke.

We studied the effect of locomotor activity on the ultrastructure of cerebellar neurons, neurological disturbances, and survival rate in Krushinsky-Molodkina rats during the development of hemorrhagic induced by acoustic stress. In animals with high spontaneous locomotor activity, severe edema of cerebellar neurons (resulting in the destruction of surrounding structures) and swelling of the synapses (terminals of mossy fibers on granule cell dendrites) were observed. By contrast, the areas of intracerebral, subdural, and subarachnoid hemorrhages were lower in rats under conditions of forced rest.

[Fusion of frog cerebellar granule cells induced by toxic effects of glutamate and NO-generating compound].

The ultrastructural changes of cerebellar granule cells were studied under stroke modeling conditions, after the toxic effects of glutamate (Glu) and NO-generating compound. Glu toxic doses were shown to induce two types of nuclear chromatin changes. In some cases, the appearance of practically completely decondensed nuclear chromatin was detected, while in the others the nuclei contained partially decondensed chromatin.