Deep Few-view High-resolution Photon-counting Extremity CT at Halved Dose for a Clinical Trial.

The latest X-ray photon-counting computed tomography (PCCT) for extremity allows multi-energy high-resolution (HR) imaging for tissue characterization and material decomposition. However, both radiation dose and imaging speed need improvement for contrast-enhanced and other studies. Despite the success of deep learning methods for 2D few-view reconstruction, applying them to HR volumetric reconstruction of extremity scans for clinical diagnosis has been limited due to GPU memory constraints, training data scarcity, and domain gap issues.

Estimation of the biomechanical mammographic deformation of the breast using machine learning models.

Background: A typical problem in the registration of MRI and X-ray mammography is the nonlinear deformation applied to the breast during mammography. We have developed a method for virtual deformation of the breast using a biomechanical model automatically constructed from MRI. The virtual deformation is applied in two steps: unloaded state estimation and compression simulation.

Ultrasound Tomography.

Ultrasound tomography (USCT) is a promising imaging modality, mainly aiming at early diagnosis of breast cancer. It provides three-dimensional, reproducible images of higher quality than conventional ultrasound methods and additionally offers quantitative information on tissue properties. This chapter provides an introduction to the background and history of USCT, followed by an overview of image reconstruction algorithms and system design.

Single-Fiber Transducer Arrays for 3-D Ultrasound Computed Tomography: From Requirements to Results.

A potential method for future breast cancer screening is 3-D ultrasound computed tomography (USCT). The utilized image reconstruction algorithms require transducer characteristics fundamentally different from conventional transducer arrays, leading to the necessity of a custom design. This design has to provide random transducer positioning, isotropic sound emission as well as a large bandwidth and wide opening angle.