[Inhibition of the repair of neutron-induced DNA single-strand breaks in experimental tumor cells].

Nicotinamide and arabinoside cytosine mixed with hydroxyurea were shown to influence the relative amount of double-stranded DNA in Ehrlich ascites tumor cells in vitro subjected to single irradiation (10-30-52 Gy) and in Guerin's carcinoma in rat lungs exposed to fractionated 6 MeV neutron-radiation (1.25 Gy X 4). The DMF values for Ehrlich ascites tumor were a function of a dose range and the duration of the drugs' effect.

[Hemodynamic features of the response to stimulation of the subcortical nuclei of the striopallidal system].

In cats, stimulation of caudate nuclei, putamen, and globus pallidus revealed a weak reactivity and excitability, low lability, inconstancy, and small alterations of the arterial pressure and heart rate as compared with the hypothalamic effects under similar conditions. These data and juxtaposition of hemodynamics and complex behavior singled out the striopallidar nuclei as a separate and relatively independent level of the centra regulation of circulation.