Publications by authors named "N V Platonova"
Article Synopsis
- The diagnosis of thyroid gland tumors is complicated, requiring specialized expertise and significant time, especially when analyzing many whole slide images from one patient.
- This paper explores using artificial intelligence, specifically a Multiple-Instance Learning model, trained on weak patient-level data from over 1100 patients to differentiate between benign and malignant cases, achieving a notable F1-Score of 0.85.
- The study highlights challenges in using real-world data, such as potential issues that could lead to model overfitting, and emphasizes that detailed annotations improve accuracy, especially in smaller datasets.
[Fulminant hypercorticism due to ACTG producing pheochromocytoma].
Probl Endokrinol (Mosk)
November 2023
Endogenous hypercorticism (EH) is a severe symptom complex caused by hypercortisolemia; according to the etiology, ACTH-dependent and ACTH-independent variants are distinguished, which, according to the literature, occur in 70-80% and 20-30% of cases, respectively. A rare cause of ACTH-dependent endogenous hypercorticism is ACTH-ectopic syndrome (ACTH-ES) (about 15-20% of cases). ACTH-ES is a syndrome of adrenocorticotropic hormone (ACTH) hyperproduction by neuroendocrine tumors of extrahypophyseal origin.
View Article and Find Full Text PDFBackground: Thyrotropin-secreting pituitary adenomas (TSH-PA) are a rare cause of thyrotoxicosis and account for 0.5-2% of all pituitary adenomas. Taking into account the rarity of the disease, it is extremely important to analyze each case of TSH-PA.
View Article and Find Full Text PDFArticle Synopsis
- * The cancer often develops due to gene mutations and is typically asymptomatic in early stages, causing a delay in diagnosis and treatment, which can lead to metastasis and further complications.
- * A clinical case highlights the unfortunate consequences of a late ACC diagnosis in a 46-year-old woman, stressing the need for better awareness and timely medical intervention for improved outcomes.