Publications by authors named "N V Nhung"
Background: Data from randomized trials evaluating the effectiveness of tuberculosis (TB) preventive treatment for contacts of multidrug-resistant (MDR)-TB are lacking. Two recently published randomized trials that did not achieve statistical significance provide the opportunity for a meta-analysis.
Methods: We conducted combined analyses of two phase 3 trials of levofloxacin MDR-TB preventive treatment - Levofloxacin for the Prevention of Multidrug-Resistant Tuberculosis (VQUIN) trial and the Levofloxacin preventive treatment in children exposed to MDR-TB (TB-CHAMP) trial.
Background: Prevention of drug-resistant tuberculosis is a global health priority. However, trials evaluating the effectiveness of treating infection among contacts of persons with drug-resistant tuberculosis are lacking.
Methods: We conducted a double-blind, randomized, controlled trial comparing 6 months of daily levofloxacin (weight-based doses) with placebo to treat infection.
Ceracris kiangsu (Tsai) (Orthoptera: Acrididae) is a severe pest of the bamboo Dendrocalamus barbatus Hsuch & D.Z. Li that is widely grown in plantations in Vietnam.
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- * The LIFT-TB project, involving 7 countries, focused on implementing BPaL under operational research conditions, aiming to assess its feasibility, effectiveness, and safety for selected DR-TB patients.
- * Interim results from November 2020 to March 2023 indicate a high treatment success rate of 90.9% among 574 enrolled patients, with manageable adverse effects and no unexpected complications, demonstrating the
Diagnostic accuracy of TB screening tests in a prospective multinational cohort: Chest-X-ray with computer-aided detection, Xpert TB host response, and C-reactive protein.
Clin Infect Dis
November 2024
Article Synopsis
- Effective diagnostic tests are crucial for detecting tuberculosis (TB) early in countries heavily affected by the disease, which led to a study screening adults with a cough in five countries.* -
- The study involved several tests, including chest X-rays and multiple screening algorithms, assessing their accuracy against microbiological standards, revealing that CAD4TB was the most reliable test.* -
- Combining different screening tests improved diagnostic accuracy, suggesting a sequential approach could better meet WHO standards for TB detection.*