Publications by authors named "N V Murthy"

In this case study, we describe a 46-year-old male presenting with a palpable, gradually enlarging scrotal mass persisting over three to four years, ultimately diagnosed as paratesticular leiomyoma, who underwent enucleation of the tumor with no signs of recurrence, two years after surgery. This report underscores the significance of accurate diagnosis to avoid unnecessary treatment. We also emphasize the sequential events and findings, supported by relevant literature review, that contributed to establishing the correct diagnosis and guiding appropriate treatment decisions.

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This case series elucidates renal cell carcinoma characterized by three distinct presentations, necessitating individualized treatment strategies tailored to each specific circumstance. The three cases presented pertain to clear cell renal cell carcinoma. The first case involves a 44-year-old male patient with renal cell carcinoma in an ectopic kidney, an exceedingly rare occurrence with limited literature.

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Lumbar hernias are a rare form of abdomen wall hernias. As this is a rare disease, treatment options are not standardized. Most case reports, even recent ones, describe open techniques.

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Introduction: A scoring system to characterize the efficacy of middle meningeal artery (MMA) embolization is lacking and would help predict the likelihood of subdural hematoma resolution.

Methods: We developed a simple angiographic classification system ranging from 0 to 3 for quantifying MMA Patency After Coil Embolization (PACE) based residual flow distal to the embolization. MMA embolizations using coils at our institution were used to validate the PACE score system using procedural angiograms.

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Article Synopsis
  • Drug delivery vectors enhance the effectiveness of therapies such as small molecules and nucleic acid drugs but face challenges in releasing therapeutic cargo in specific conditions.
  • Recent advancements focus on creating acid-degradable and enzyme-cleavable linkages for better performance in endolysosomal release.
  • Key innovations include stable azido-acetal linkers, organocatalytic methods for making asymmetric ketals, and linkers activated by enzymes like cathepsin B and β-galactosidase for improved drug delivery.
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