Publications by authors named "N V Michalopoulos"
Physical Activity Component of the Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER): Protocol Development and Feasibility Study.
Healthcare (Basel)
November 2024
Article Synopsis
- Individuals with subjective cognitive decline (SCD) face a higher risk of developing dementia, and the GINGER initiative presents a multicomponent lifestyle intervention approach that includes exercise as a key component for prevention and management.
- The exercise protocol designed for GINGER targets adults over 55 with SCD and involves a structured program of aerobic, strengthening, balance, and dual-task exercises, delivered three times a week, both in group sessions and at home.
- The implementation of this exercise protocol was found to be feasible and reliable, showing good adherence and user satisfaction, along with notable improvements in physical health outcomes among participants.
Diffuse lipomatosis of the thyroid (DLT) is an uncommon condition where mature fat cells infiltrate the thyroid gland, disrupting its normal structure. Although rare, it typically manifests as neck enlargement or symptoms of compression, including breathing difficulties, trouble swallowing, and voice changes, which can complicate diagnosis. This report presents a case of a 61-year-old woman with DLT, who exhibited a multinodular goiter and progressive neck swelling, and examines 53 additional cases from the existing literature.
View Article and Find Full Text PDFBackground/aim: The molecular classification of breast cancer has enabled targeted therapy for specific molecular subtypes. Nestin, which has been studied for its role in oncogenesis, could contribute to this direction. This study aimed to investigate the differences between serum nestin levels and molecular profiling, as well as histopathological tumor types, in women who underwent surgery for breast cancer.
View Article and Find Full Text PDFIntroduction: Endometriosis is a common benign condition affecting 10-15% of women of reproductive age. An unusual site of endometriosis is the canal of Nuck, which is a physiologically obliterated space in women spanning the area from the deep inguinal ring to the labia majora.
Case Presentation: A 37-year-old woman, with a past medical history of several in vitro fertilization attempts, presented with a right-sided painful inguinal mass.
Objectives: There is extensive evidence to support the use of FIBTEM to identify hypofibrinogenemia during cardiac surgery, but less to support the use of EXTEM and INTEM clotting times (CTs) to identify other plasmatic coagulation factor deficiencies. The aim of the current study was to assess the diagnostic accuracy of EXTEM, INTEM, and HEPTEM CTs, using laboratory international normalized ratio (INR) and activated partial thromboplastin time (aPTT) as reference standards.
Design: This was a retrospective diagnostic accuracy study.