[Alveolar adenoma of the lung].

Alveolar adenoma of the lung is a rare benign tumor first described in 1986. This article presents an observation of alveolar adenoma in a 72-year-old woman. Morphological and immunohistochemical methods of tumor diagnostics, issues of differential diagnosis are analyzed.

Artificial intelligence (AI) for tumor microenvironment (TME) and tumor budding (TB) identification in colorectal cancer (CRC) patients: A systematic review.

Evaluation of the parameters such as tumor microenvironment (TME) and tumor budding (TB) is one of the most important steps in colorectal cancer (CRC) diagnosis and cancer development prognosis. In recent years, artificial intelligence (AI) has been successfully used to solve such problems. In this paper, we summarize the latest data on the use of artificial intelligence to predict tumor microenvironment and tumor budding in histological scans of patients with colorectal cancer.

Digital twin concept: Healthcare, education, research.

Introducing the concept of digital twins in healthcare, medical education, and research is a complex multistage challenge requiring participation of multidisciplinary teams. In pursuing this goal, we have created a validated database of scans of colorectal tumor slides associated with relevant clinical and histological information. This database is also linked to the blood bank, which opens a wide range of opportunities for further research.

[Diagnosis and treatment of placental insufficiency in patients with congenital heart defects].

The fetoplacental system was studied in 80 patients with congenital heart disease by placental scintigraphy, cardiotocography, and ultrasonic examination. Disordered uteroplacental blood flow was detected in 52 of the 64 patients, small-for-date fetuses in 36 of the 80, and chronic fetal hypoxia in 48 of the 72 patients. The authors come to a conclusion that a congenital heart disease is a risk factor in respect of placental insufficiency development.

[Diagnosis of placental insufficiency in patients with acquired heart defects].

The feto-placental unit has been evaluated in 102 patients with acquired heart disease presenting as different circulatory states (Grade 0 insufficiency in 43, Grade I in 34 and Grade II A-B in 25 women). Placental scintigraphy was performed in 102, cardiotocography in 77, ultrasonographic fetal and placental biometry in 102 and placental pathological examination in 15 women. The neonatal study included 104 infants, with 2 twin pairs.