Publications by authors named "N V Khaĭtovych"

Objective: The aim: Objective of the research is to determine the effect of NOS3 and AGTR1 genotypes of patients with arterial hypertension and high body mass index in the course of the disease.

Patients And Methods: Materials and methods: 58 patients (22 men and 36 women) with AH and high BMI were examined. The average age of the examined patients was 53.

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Investigation of phenotypic realization of the eNOS gene allelic polymorphism has shown that eNOS RNA content and eNOS activity in platelets depends on genotype. Using the reverse transcription and polymerase chain reaction it was shown that eNOS mRNA content is the lowest at -786C/C promoter's genotype. In exon 7 homozygotes (894T/T) the RNA level is lower than in normal homozygotes (894G/G), but it is higher than in heterozygotes (894G/T).

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