Psoriasis and the pregnant woman: what are the key considerations?

Pregnancy is characterized by multiple physiologic changes. During the entire gestational period, both mother and infant are vulnerable to a variety of external and internal factors. Maternal disease, use of certain medications, drugs, alcohol, smoking, and radiation exposure can have devastating effects on the fetus.

Alcohol and skin disorders: with a focus on psoriasis.

Alcohol is a serious cause of morbidity and mortality in our society and is implicated in multiple health conditions, including hepatic failure, neurological damage, hematological disorders, and nutritional deficiencies, to name a few. Although alcohol induced cutaneous abnormalities can also cause significant morbidity, they tend to be overshadowed by the other disease states associated with alcohol use. In addition to the cutaneous stigmata linked to chronic alcoholic liver disease, alcohol can directly cause or exacerbate several skin conditions.

Resolution of odontogenic keratocysts of the jaw in basal cell nevus syndrome with GDC-0449.

Background: Odontogenic keratocysts of the jaw are a central feature of basal cell nevus syndrome (BCNS) and arise from the basal cell layer of the surface epithelium. Although they are benign, they tend to be aggressive, with local invasion of bony structures, extensive growth, and potential for substantial disfigurement and speech dysfunction. Complete surgical resection is the current standard of care; however, the procedures are often technically challenging and are followed by high recurrence rates.

[Assessment of effectiveness of immunization against Hib-infection].

Aim: To assess effectiveness of Act-HIB vaccine forprevention of acute respiratory diseases.

Materials And Methods: Nine hundred immunized children 1 - 5 years old as well as not immunized children of the same age were followed-up. Criteria for clinical effectiveness of the vaccine were rate of acute respiratory infection episodes, duration of disease episode, and rate of complications development.