[On theory of sensory conflict under exposure to physical factors: main principles and concepts of formation].

The article presents results of longstanding studies on influence of occupational physical factors on workers health. Experimental and nature studies helped to justify basic concepts of sensory conflict theory, a trigger of occupational disease formation. Patients having occupational disease present disorders of cortex-subcortex relationships on diencephal level, central and peripheral regulatory mechanisms, central sensory mechanisms participation in pathologic processes development, changes in vegetative regulation on cerebral level, demyelination and axon demyelination changes in peripheral nerves of upper and lower limbs.

[Dynamics of morphofunctional state of central nervous system in white rates exposed to vibration].

The authors presented results of experimental studies assessing influence of vibration on white rats. Dynamics of morphologic changes development in brain of experimental animals exposed to vibration were shown. Exposure to vibration in white rats daily during 4 hours over 15 days causes astrogliosis--compensation process in response to brain injury; over 1 month--causes morphologic brain changes (vacuoles formation in neuropile, decrease in astroglia cells number); over 2 months--causes lower plasticity of brain neurons, preserved astrogliosis; over 4 months--causes perivascular edema.

[Bioelectric brain activity under exposure to vibration].

Patients with vibration disease caused by local vibration and those with the disease caused by general vibration demonstrate similar changes in regulation of central nervous system, as shown by EEG--diffuse changes and locus of pathologic activity mostly in right temporal cortex. Unlike local vibration, the combined one acting long (over 10-15 years) causes more pathologic changes in brain, not only in cerebral cortex, but also in brainstem and diencephalic structures.

[Topographic mapping in comparative evaluation of brain electric activity in individuals with occupational vs. somatic diseases].

The authors presented results of topographic mapping and comparative evaluation of EEC patterns in patients with occupational and non-occupational diseases, apparently healthy individuals. Findings are unidirectional changes in EEC parameters among occupational diseases patients.