Percutaneous Exposures of volunteers to polychromatic light (480-3400 nm) trigger systemic mechanism of the human myeloma cells growth delay without any effect on bortezomib cytotoxicity in vitro.

Background And Aim: Polychromatic light is actively used in medicine. However, its oncological safety and effect against cytotoxic therapy remains poorly studied. Multiple myeloma (MM) develops in the bone marrow and therefore malignant plasma cells are inaccessible to direct exposure to light.

[Contribution of older age groups to life expectancy changes in Russian megacities (the case of Moscow and Saint-Petersburg).].

Dynamics of life expectancy at birth (LE0) and at older ages has been analyzed and the contribution of older ages (60+) to the life expectancy changes has been estimated for greatest Russian megacities Moscow and Saint-Petersburg. The contributions of aggregated age groups to differences of LE0 values for Moscow and Saint-Petersburg have been studied. It has been found, in particular, that the increase in life expectancy at older ages makes a significant contribution to the LE0 growth.

[Therapeutic Effects of Multipotent Mesenchymal Stromal Cells after Irradiation].

Multipotent mesenchymal stromal cells (MSC) are now considered to be a perspective multifunctional treatment option for radiation side effects. At present.a great number of sufficient evidence has been collected in favor of therapeutic effects of MSCs in acute radiation reactions.

[Structural changes of the adrenal cortex in experimental genital herpes virus infection].

The reactive changes in the adrenal gland cortex were studied in mature female guinea pigs (n=5) in an experimental model of acute genital herpes virus infection. The methods of light and transmission electron microscopy were used. To confirm the presence of viral antigen in the corticosterocytes (CSC), the methods of immunfluorescence and electron microscopic immunocytochemistry were used.

Comparative characteristics of platelet lysates from different donors.

We studied the effect of platelet lysates from different donors on fibroblast growth in culture. In most samples (40 of 50), the growth-stimulating characteristics were greater than in 10% FCS, but every ninth sample exhibited low mitogenic activity. A weak dependence between platelet concentration and total protein content was noted, but no correlation was found between these parameters and fibroblast growth in culture.