[Structural-functional characteristics of Yersinia pseudotuberculosis plasmid pVM82].

The restriction map of Yersinia pseudotuberculosis plasmid pVM82 was established using the "chromosome walking" method. According to transpositional mutagenesis, the plasmid pVM82 appeared to be conjugative and was able to be transmitted from Y. pseudotuberculosis to the E.

[Study of polymorphism of strains of Vibrio cholerae of various origins using a method of genomic fingerprinting].

Population of atoxigenic Eltor vibrios (vct-) isolated from open water has been shown to be heterogeneous by the genomic fingerprinting technique. Epidemically dangerous strains (vct+) containing the gene coding for cholera toxin have similar hybridization profile independent of time and place of their isolation. The clonal formation of vct+ strains and the absence of vct----vct+ transition of strains under natural conditions are discussed.

[Analysis of the plasmid composition of Yersinia pseudotuberculosis strains and its use for typing pseudotuberculosis pathogens].

Electrophoresis in agarose gel has been used to study the plasmid spectra of 854 Yersinia pseudotuberculosis strains isolated from different sources. The plasmids found in the microbial strains are represented by the elements with molecular masses 82; 57; 45; 5.5; 4.

[Integration with the chromosome--an alternative state of calcium-dependency plasmids in Yersinia].

Using the technique of the genes probes the naturally occuring strains Y. pseudotuberculosis and Y. enterocolitica of epidemiological importance were shown to contain pCad plasmid integrated with the chromosome.

[A new pathogenic trait encoded by Yersinia pseudotuberculosis pVM82 plasmid].

The strains of Yersinia pseudotuberculosis isolated from patients in the course of outbreaks of infection (epidemic strains) were found to possess at least two plasmids with molecular masses of 45 and 82 MD. In contrast, the strains obtained in sporadic cases harbored different sets of plasmids, but never the 82 MD plasmids. These plasmids designated pVM82 and isolated from strains of different geographic regions of the country were identical.