[Treatment of patients with B-small cell lymphoma using R-CHOP protocol].

Non-Hodgkin's lymphoma is one of the most challenging problems in modern oncology. Creation of drugs inhibiting specifically intracellular signal tracks which being activated in its turn lead to oncogenes hyperexpression and inactivating other genes responsible for suppression of oncogenes, leading eventually to a cell's constant proliferation. This method is a new approach for cancer treatment.

[Role of etiol (amifostine) in the treatment of patients with malignant lymphoma].

The material is devoted to using of amifostinum as cytoprotor during polychemotherapy application in patients with malignant lymphomas. 10 patients (5 with lymphogranulomatosis, 4 with non-Hodgkin's lymphoma and 1 with Ewing's sarcoma) were receiving along with cytostatic therapy amifostinum. The patients treated with combined therapy had less side effects of polychemotherapy than a control group which had been receiving only polychemotherapy.