Current State and Challenges of Tissue and Organ Cryopreservation in Biobanking.

Recent years have witnessed significant advancements in the cryopreservation of various tissues and cells, yet several challenges persist. This review evaluates the current state of cryopreservation, focusing on contemporary methods, notable achievements, and ongoing difficulties. Techniques such as slow freezing and vitrification have enabled the successful preservation of diverse biological materials, including embryos and ovarian tissue, marking substantial progress in reproductive medicine and regenerative therapies.

Enhancing decellularized vascular scaffolds with PVDF and PCL reinforcement: a fused deposition modeling approach.

Background: Decellularized xenogenic scaffolds represent a promising substrate for tissue-engineered vascular prostheses, particularly those with smaller diameters (<6 mm). Despite their benefits, a notable limitation presents itself during decellularization, namely, the diminished mechanical strength that introduces the risk of aneurysmal dilations in the early post-implantation period. This study introduces a strategy for modification the mechanical properties of these biological scaffolds through the forming of an external polymeric reinforcement via thermal extrusion.

Numerical modeling of the impact on the vascular wall during endovenous ultrasound treatment.

The article describes the research of a new treatment method of lower limb varicose vein using low-frequency ultrasound. To study the effectiveness of this method we analyzed the interaction between the ultrasound instrument and the venous wall and defined the mechanisms of action during endovenous ultrasound treatment (EUT): thermal, mechanical, and chemical. We developed three models to study the impact of different combinations of mechanisms of action on varicose venous wall.

Mechanism of Vascular Injury in Transcatheter Aortic Valve Replacement.

Unlabelled: was to determine the potential mechanism of vascular complications due to "catheter-vascular wall" interaction in transcatheter aortic valve replacement using experimental and numerical analysis.

Materials And Methods: A series of full-scale bench tests and numerical simulations were carried out using the CoreValve commercial transfemoral delivery system for aortic valve bioprosthesis (Medtronic Inc., USA).

Biomechanical properties of the anterior lens capsule after manual and femtolaser capsulotomy.

Purpose: To comparatively evaluate the mechanical stability of the edge of central fragment of anterior lens capsule after manual and femtolaser capsulotomy.

Material And Methods: The mechanical tests were performed on the central fragments of the anterior lens capsules obtained intraoperatively after manual and femtolaser capsulotomy (15 and 13 samples, respectively). The conditions of the developed method of mechanical testing are as close to in vivo as possible.