Publications by authors named "N V Baymeeva"
[Therapeutic drug monitoring of antipsychotic drugs in routine psychiatric practice].
Zh Nevrol Psikhiatr Im S S Korsakova
June 2023
Objective: To evaluate the relationship between daily doses of antipsychotic drugs, their serum concentrations, and characteristics of patients treated for schizophrenia or schizophreniform disorder in day-to-day clinical practice.
Material And Methods: A total of 187 patients were included in the study, 77 (41.1%) patients were on monotherapy, and 110 (58.
[Cinnabarinic acid as a potential prognostic marker of schizophrenia].
Zh Nevrol Psikhiatr Im S S Korsakova
December 2022
Objective: To develop a method for determining cinnabarinic acid (CA) and its immediate precursor 3-hydroxyanthranylic acid (3HAA) in blood plasma and to study their concentrations in patients with schizophrenia before and after treatment.
Material And Methods: The study was carried out on a sample of 23 female patients with an attack-like progredient schizophrenia (F20.01).
[Therapeutic drug monitoring of aripiprazole as part of the individualization of the pharmacotherapy of schizophrenia].
Zh Nevrol Psikhiatr Im S S Korsakova
February 2022
Objective: To personalize pharmacotherapy with aripiprazole in patients with schizophrenia via therapeutic drug monitoring (TDM).
Material And Methods: TDM of aripiprazole (ARI) and its active metabolite dehydroaripiprazole (DHA) was performed for patients diagnosed with schizophrenia (ICD-10 F20.00; F20.
Background: The relationship between a daily dose of olanzapine, its serum concentration, and the genotype of young nonsmoking men treated for schizophrenia or schizophreniform disorder was investigated in day-to-day clinical practice. Pharmacogenetics was also examined for the selected patients.
Methods: A total of 49 participants were recruited as in-patients at the Mental Health Research Center (Moscow, Russia).
Article Synopsis
- - The study investigates the effects of sub-chronic haloperidol (Hal) administration on the innate immune system in healthy rats, revealing a two-fold decrease in the activity of the complement system and hemostasis after 3 weeks of treatment.
- - Results show that Hal levels correlate with various immune parameters such as the phagocytic activity of macrophages and enzymatic activities, suggesting significant immunotoxic effects.
- - Hal also alters macrophage behavior, promoting an "anti-inflammatory" phenotype and impacting both phagocytic function and antioxidant enzyme activity, indicating complex biological interactions and potential health risks.