A Case of Idiopathic Twenty-Nail Dystrophy.

In children, nail diseases can be either congenital or acquired, with an occurrence rate of 3 to 11% in the pediatric population. In both fingers and toes, rough, accentuated linear ridges of the nails are referred to as trachyonychia. This condition most commonly occurs in childhood, with a higher prevalence in males.

Edward Jenner: A Beacon of Hope in the Age of Disease.

Edward Jenner, born in 1749 in Berkeley, Gloucestershire, England is widely recognized as the pioneer of the smallpox vaccine, a breakthrough that paved the way for the eventual eradication of the disease. This article traces Jenner's journey from his early education and apprenticeship under renowned surgeon John Hunter to his groundbreaking work on vaccination. Jenner's keen observations led him to hypothesize that cowpox could provide immunity against smallpox, which he confirmed through an experiment in 1796.

A Syndrome Affecting All Five Sense Organs: A Rare Congenital Disorder of Kabuki Makeup Syndrome With Multiple Pre-auricular Skin Tags.

Kabuki syndrome is an autosomal dominant disorder characterized by distinct facial features, including long palpebral fissures, a short columella with a flat, broad nasal tip, ptosis, and cleft lip/palate. The syndrome was named for the resemblance of the facial features to the make-up worn by traditional Kabuki performers. We report the case of a 10-month-old female infant admitted for cleft palate repair.

Impact of Nadi Shuddhi Pranayama on Apnea Hypopnea Index, Respiratory Distress Index, and Oxygen Desaturation Index Among Adolescents With Sleep Apnea Syndrome.

Background Sleep apnea syndrome has gained significant recognition over the last decade as a potential cause of substantial childhood morbidity. This study aimed to evaluate the impact of the Apnea Hypopnea Index (AHI), Respiratory Distress Index (RDI), and Oxygen Desaturation Index (ODI) among adolescents with sleep apnea syndrome. Objectives The objective of this study is to compare the impact of Nadi Shuddhi Pranayama with routine treatment modalities on the AHI, RDI, and ODI among adolescents with sleep apnea syndrome.

An unusual case of Pseudohypoaldosteronism coexisting with cystic fibrosis.

Pseudohypoaldosteronism type 1 is a rare congenital autosomal recessive disorder, characterised by failure of receptor response to aldosterone. It is caused by mutation in SCNN1A gene with clinical features like failure to thrive in infancy, hyponatraemia, hyperkalaemia and metabolic acidosis. We present a male infant with seizures, hyperkalaemia and with failure to thrive, diagnosed at day 6 of life.