Publications by authors named "N Tzanakis"

Remission of asthma can occur as part of the natural history of the disease; however, the use of biologics can result in disease remission in some patients. In this post hoc analysis of the RELIght study, we aimed to evaluate clinical remission in real life among patients treated with mepolizumab, to detect possible differences between "remitters" and "nonremitters," and to evaluate possible predictors of remission. Clinical remission was defined as the absence of asthma exacerbations, discontinuation of oral corticosteroids (OCS), achievement of asthma control (Asthma Control Test [ACT] ≥ 20), and stable or improved lung function.

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Article Synopsis
  • Obstructive sleep apnea (OSA) often occurs alongside idiopathic pulmonary fibrosis (IPF), and specific biomarkers like KL-6, ET-1, and S100A9 may help in diagnosing and understanding the severity of these conditions.
  • A study involving 55 participants, including those with IPF and IPF-OSA, measured these biomarker levels and examined their relationship with various health factors.
  • Although no significant differences in biomarker levels were found between groups, there were trends suggesting higher ET-1 in IPF-OSA, and significant correlations between KL-6 levels and IPF severity, indicating potential for these biomarkers in identifying OSA impact in IPF patients.
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Background: Implementing asthma guideline recommendations is challenging and there is variation between countries, and different healthcare professionals (HCPs). The International Primary Care Respiratory Group (IPCRG) has introduced the Asthma Right Care (ARC) programme implemented in 24 low, middle, and high countries, including Greece. It offers a promising approach drawn from social movements for health to improve asthma care by engaging HCPs in implementing guideline-based asthma care.

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Respiratory disorders significantly impact adolescents' health, often resulting in hospital admissions. Meteorological elements such as wind patterns have emerged as potential contributors to respiratory symptoms. However, it remains uncertain whether fluctuations in wind characteristics over extended periods have a tangible impact on respiratory health, particularly in regions characterized by distinct annual wind patterns.

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