Publications by authors named "N Toyoshima"

Article Synopsis
  • A new technique called underwater injection EMR (UI-EMR) was developed to improve the removal of submucosal tissue in T1 colorectal cancer (T1-CRC) while ensuring adequate margins.
  • A study involving 135 patients showed that UI-EMR achieved a high success rate in resection, with en bloc success in 94.1% of cases and minimal adverse events.
  • The method also resulted in sufficient vertical margins for all evaluated T1-CRCs, suggesting it could be a favorable option for treating small non-pedunculated colorectal polyps that are concerning for T1-CRC.
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Background And Aim: Colorectal endoscopic submucosal dissection is a technically demanding procedure with a steep learning curve. In Japan, the National Cancer Center Hospital allows overseas doctors to participate in hands-on training. We aimed to assess the colorectal endoscopic submucosal dissection performance and learning curve of an endoscopist who participated in hands-on training.

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Background: Endoscopic resection techniques for colorectal tumors are constantly evolving with improvements.

Summary: Over the past decade, there has been a paradigm shift toward cold polypectomy for the removal of small lesions (<10 mm), known as the "cold revolution". In recent years, underwater endoscopic mucosal resection (EMR) has emerged as an alternative to conventional EMR and has been gaining popularity for resection of intermediate and large-sized lesions (≥10 mm).

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Article Synopsis
  • Endoscopic hand suturing (EHS) is a new method for closing mucosal defects after endoscopic submucosal dissection (ESD), and this study aimed to evaluate its technical feasibility in colorectal procedures using a modified needle holder.
  • Conducted at two referral centers, the study included 20 patients with colorectal neoplasms, revealing a high complete closure rate of 90% and an average suturing time of 49 minutes.
  • The results indicated an 85% sustained closure rate on follow-up endoscopy, with no delayed adverse events, highlighting EHS's effectiveness but suggesting it may be best suited for high-risk cases due to its complexity and time requirements.
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Colonoscopy is the gold standard for detecting and resecting adenomas or early stage cancers to reduce the incidence and mortality rates of colorectal cancer. In a recent observational study, texture and color enhancement imaging (TXI) was reported to improve polyp detection during colonoscopy. This randomized controlled trial involving six Japanese institutions aims to confirm the superiority of TXI over standard white-light imaging (WLI) in detecting colorectal lesions during colonoscopy.

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