Publications by authors named "N Tomaru"

Article Synopsis
  • Surgical treatment for diabetic foot ulcers (DFU) or chronic limb-threatening ischemia (CLTI) is complicated due to patients' poor health, making general anesthesia risky; therefore, peripheral nerve block with dexmedetomidine sedation is used in this study.
  • The study involved 18 patients and assessed sedation levels, intraoperative stress, and memory using various scales, showing effective sedation and low stress levels during surgery, though some patients experienced hypoxemia.
  • The findings indicate that using peripheral nerve block with dexmedetomidine can reduce patient stress and anxiety during surgery, but the potential for hypoxemia should be monitored closely.
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  • Necrotizing fasciitis (NF) is a severe and rapidly spreading infection that can be deadly, but negative pressure wound therapy (NPWT) has shown effectiveness in aiding wound healing despite its risk of infection.
  • Continuous local antibiotic perfusion (CLAP) is an innovative method that delivers high levels of antibiotics directly to the infected area via NPWT, utilizing techniques like intramedullary and intra-soft tissue antibiotic perfusion.
  • Two cases of lower extremity NF treated with intra-soft tissue antibiotic perfusion (iSAP) demonstrated successful infection control and faster wound healing, highlighting iSAP as a promising treatment option with a shorter treatment duration for patients.
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Article Synopsis
  • Pyogenic myositis is a bacterial infection of skeletal muscle, commonly caused by Staphylococcus aureus, but can also occur in immunocompromised patients, particularly in tropical regions.
  • An 82-year-old Japanese man with type 2 diabetes experienced severe pain and swelling in his chest, leading to a diagnosis of pectoralis major pyomyositis caused by Morganella morganii after various tests ruled out other conditions.
  • The patient underwent surgical debridement and had a successful recovery, highlighting the need for prompt intervention as antibiotics alone may not be sufficient to treat this infection.
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The reduced growth performance of individuals from range edges is a common phenomenon in various taxa, and considered to be an evolutionary factor that limits the species' range. However, most studies did not distinguish between two mechanisms that can lead to this reduction: genetic load and adaptive selection to harsh conditions. To address this lack of understanding, we investigated the climatic and genetic factors underlying the growth performance of Betula ermanii saplings transplanted from 11 populations including high-altitude edge and low-latitude edge population.

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Premise: The formation of isolated montane geography on islands promotes evolution, speciation, and then radiation if there are ecological changes. Thus, investigating evolutionary histories of montane species and associated ecological changes may help efforts to understand how endemism formed in islands' montane floras. To explore this process, we investigated the evolutionary history of the Rhododendron tschonoskii alliance, which grows in montane environments of the Japanese archipelago and the Korean Peninsula.

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