Publications by authors named "N Tisavipat"

Objectives: To report myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) epidemiology in two American regions using 2023 diagnostic criteria.

Patients And Methods: We compared age- and sex-adjusted incidence and prevalence of MOGAD per 2023 diagnostic criteria in Olmsted County (Minnesota [USA]) and Martinique (Caribbean [FR]) (01/01/2003-12/31/2018, prevalence day) using Poisson regression. Archived sera in 68-85% were available for MOG-IgG testing by live cell-based assay at Mayo Clinic.

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Article Synopsis
  • This review article highlights global advancements in neuro-ophthalmology, specifically focusing on innovative diagnostic and therapeutic techniques shaping the field's future.
  • Key developments include the vital role of optical coherence tomography (OCT) for understanding optic nerve and central nervous system issues, as well as the promise of gene therapy for conditions like Leber's hereditary optic neuropathy.
  • The article also explores the impact of telemedicine and artificial intelligence in patient care, along with emerging biomarkers and new treatments such as Tocilizumab and Teprotumumab, enhancing the approach to managing conditions like immune-mediated optic neuritis.
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Purpose: This study aimed to determine whether magnetic resonance imaging (MRI) biomarkers are associated with visual prognosis in myelin oligodendrocyte protein (MOG)-associated optic neuritis (ON).

Design: Cross-sectional analysis.

Participants: Patients meeting 2023 international diagnostic criteria for MOG antibody-associated disease who were seen for first episodes of MOG-associated ON at 3 tertiary neuro-ophthalmology practices between January 2017 and July 2023 were enrolled.

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Article Synopsis
  • The study applied the 2022 international consensus criteria for optic neuritis (ICON) to 160 patients with acute optic neuritis to assess its effectiveness in classification.
  • About 50% of the patients were classified as definite optic neuritis, while 43% were not classified as having ON, mainly due to the absence of critical symptoms like relative afferent pupillary defect (RAPD) and dyschromatopsia.
  • The adjusted criteria led to a higher classification of 79% of patients as having optic neuritis, highlighting the importance of thorough examinations for accurate diagnosis.*
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