Publications by authors named "N Thiruchelvam"
CATHETER II: a randomised controlled trial comparing the clinical effectiveness of various washout policies versus no washout policy in preventing catheter-associated complications in adults living with long-term catheters.
BMJ Open
December 2024
Objectives: Do weekly prophylactic saline or acidic catheter washouts in addition to standard long-term catheter (LTC) care improve the outcomes of adults with LTC compared with standard LTC care only.
Design: Three-arm superiority open-label randomised controlled trial.
Setting: UK community-based study.
Background: Clean intermittent self-catheterisation (CISC) with conventional eyelet catheters (CECs) is associated with urine flow-stops, which require the catheter to be repositioned so flow can resume. Flow-stops often occur because bladder mucosa is sucked into the eyelets.
Aims: This investigation aimed to compare the bladder-emptying performance of the micro-hole zone catheter (MHZC) with the CEC.
Article Synopsis
- - The SATURN registry, a European multicenter study, aims to evaluate the effectiveness of surgical devices for treating male stress urinary incontinence, focusing on cure rates during a 10-year follow-up, with 1-year results currently reported.
- - The study involved 1,046 male patients, primarily post-radical prostatectomy, using various implants like AMS800 and Advance, and showed varying self-reported continence rates—ranging from 11% to 76% depending on the device, with 32% of patients still experiencing incontinence after one year.
- - Patient-reported outcomes indicated improvements in quality of life, but a notable percentage of patients required revisions of their devices, suggesting complications remained a concern
Aims: To confirm the improved performance of the micro-hole zone catheter (MHZC) compared to a conventional eyelet catheter (CEC) in male users of clean intermittent catheterizations (CICs).
Methods: Male self-catheterizing subjects, who used hydrophilic sleeved soft/flexible CIC as the only bladder emptying method, were enrolled into a multi-center, randomized, cross-over study performed across six European sites. Subjects tested the MHZC, featuring a drainage zone with 120 micro-holes and a CEC with two eyelets.
Objective: To examine the safety and efficacy of prostatic urethral lift (PUL) in acute urinary retention (AUR) patients within a controlled (PULSAR) and real-world setting (Real-World Retrospective study).
Materials And Methods: PULSAR was a 12-month prospective study of PUL in AUR patients ( = 51) performed at six centres in the United Kingdom; enrolled BPH patients aged ≥50 years, with prostate volume of ≤100 cc. AUR was defined as being catheter dependent with at least one prior failed trial without catheter (TWOC) while on an alpha-blocker.