Inhibition Mechanism of Components Isolated from Branches on Diabetes and Diabetic Complications via Experimental and Molecular Docking Analyses.

Previously, we reported the anti-diabetic effect of root bark and the compounds therein. In our continuous study of other parts of this plant, the ability of the branch of to inhibit α-glucosidase, protein tyrosine phosphatase 1B (PTP1B), and advanced glycation end products (AGEs) formation was evaluated. Moreover, there are no previous studies that have performed enzyme kinetics and molecular docking analyses, along with assessments of peroxynitrite (ONOO) inhibitory activities.

Transcriptome Assembly of Sheds Light on the Anthraquinone Biosynthesis Pathway.

is an annual leguminous herb that is rich in anthraquinones, which have various pharmacological activities. However, little is known about the genetics of , particularly its anthraquinone biosynthesis pathway. To broaden our understanding of the key genes and regulatory mechanisms involved in the anthraquinone biosynthesis pathway, we used short RNA sequencing (RNA-Seq) and long-read isoform sequencing (Iso-Seq) to perform a spatial and temporal transcriptomic analysis of .

Mobile Phone: A Possible Vector of Bacterial Transmission in Hospital Setting.

Background Mobile phones of Health Care Workers (HCWs) are capable of harbouring microorganisms that can potentially cause nosocomial infections. Frequent movement of hospital staff inside and outside the hospital can augment bacterial transmission inside hospital and even to the community. Objective To screen the mobile phones of Health Care Workers for potential pathogens and perform microbiological study of the isolates.