Publications by authors named "N Taudon"
Article Synopsis
- Plasmodium falciparum, the deadly malaria-causing parasite, has shown resistance to dihydroartemisinin-piperaquine, a recommended treatment, first noted in Southeast Asia and suspected in South America.* -
- A study in French Guiana found that 47% of tested P. falciparum cases were resistant to piperaquine, with specific genetic markers like pfCRT and pfpm2/pfpm3 amplifications strongly linked to this resistance.* -
- The prevalence of these resistance markers varies regionally, with especially high rates in Suriname and Guyana, and shows a different pattern of genetic evolution compared to Southeast Asia, indicating unique geographical influences on resistance development.*
Article Synopsis
- A case study of an obese patient who faced treatment failure on day 28 after being treated for severe malaria with artesunate and dihydroartemisinin-piperaquine (DHA-PPQ).
- The same malaria strain was identified at the start of treatment (day 0) and after 28 days.
- While resistance tests didn't reveal reasons for the treatment failure, low levels of piperaquine in the patient's plasma might have contributed to ineffective elimination of leftover parasites.
Introduction: Depending on the individual, exposure to an intense stressor may, or may not, lead to a stress-induced pathology. Predicting the physiopathological evolution in an individual is therefore an important challenge, at least for prevention. In this context, we developed an ethological model of simulated predator exposure in rats: we call this the multisensorial stress model (MSS).
View Article and Find Full Text PDFAntibacterial resistance is a healthcare burden. Among Gram-negative bacteria, Pseudomonas aeruginosa belongs to the first list of antibiotic-resistant "priority pathogens" described by the World Health Organization. Formerly Pseudomonas pseudomallei, Burkholderia pseudomallei, responsible for melioidosis, is considered as a potential bioterrorist weapon by the Centers of Diseases Control and Prevention.
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