Canadian medical schools before ACMC.

The earliest medical schools were established to supplement apprenticeship, the only route to practice available in colonial Canada. By 1885, eight medical schools were trying to accommodate the volume of new scientific information flowing from Europe. In 1910, when Flexner evaluated the schools against the Johns Hopkins model, some were woefully deficient, but by 1928 all had achieved Class A rating.

Intermediary metabolism in diabetic dogs treated with pancreatic autotransplants and insulin pumps.

Diurnal metabolite profiles were studied in pancreatectomized dogs who had received grafts of their own pancreas. The results were compared to similarly diabetic animals who received exogenous insulin pumped intravenously either peripherally or portally. All animals were studied at least 52 weeks after pancreatectomy.

Metabolic control in diabetic dogs treated with pancreatic autotransplants and insulin pumps.

Fasting metabolite and hormonal levels were studied prospectively in pancreatectomized dogs who had received grafts of their own pancreas. The results were compared with similarly diabetic animals who received exogenous insulin pumped intravenously either peripherally or portally. All animals were studied for 48-91 wk after pancreatectomy.

Glycemic control in diabetic dogs treated with pancreatic autotransplants and insulin pumps.

The restoration of metabolic control in diabetes mellitus is predicated upon the uniform achievement of fasting euglycemia. In the absence of fasting normoglycemia, metabolic control is fundamentally compromised. We asked whether the currently experimental methods of treating experimental diabetes are capable of achieving normality in this regard.