Publications by authors named "N T LUONG"

Article Synopsis
  • Pancreatic ductal adenocarcinoma (PDAC) is characterized by a rigid extracellular matrix (ECM) that has specific properties like high stiffness and a quick ability to relax from stress, which this study aims to replicate using gelatin-based hydrogels.
  • The researchers created these hydrogels with varying stiffness and stress relaxation by manipulating the cross-linking methods and materials, allowing them to better mimic the conditions found in PDAC tissues.
  • Experiments showed that the fast-relaxing hydrogels promoted PDAC cell growth and other cancer traits, and blocking a certain protein (integrin β1) changed tumor behavior, suggesting integrin β1 could be a potential target for improving cancer treatment
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Article Synopsis
  • The study examines how behavioral data from smartphones can be used to detect and monitor depression symptoms in patients.
  • Researchers collected smartphone data from 164 participants over a year, including both healthy individuals and patients with various depressive disorders.
  • The analysis revealed 32 key behavioral markers linked to depression, achieving an 82% accuracy in classifying depressed individuals and 75% accuracy in tracking changes in their depressive states.
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Introduction: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions. However, only a few studies have investigated the clinicodemographic and laboratory parameters predicting SJS and TEN outcomes other than mortality, such as severe complications or increased length of hospital stays. Our objectives are to identify admission risk factors predictive of severe complications and the accompanying clinical or biochemical markers associated with prolonged hospitalization.

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Decellularized small intestine submucosa (dSIS) is a promising biomaterial for promoting tissue regeneration. Isolated from the submucosal layer of animal jejunum, SIS is rich in extracellular matrix (ECM) proteins, including collagen, laminin, and fibronectin. Following mild decellularization, dSIS becomes an acellular matrix that supports cell adhesion, proliferation, and differentiation.

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Introduction: Several COVID-19 outbreaks have been reported in meat processing plants in different countries. The aim of this study was to assess the environmental and socio-economic risk factors favouring the transmission of SARS-CoV-2 in meat processing plants and to describe the prevention measures implemented.

Methods: Data from epidemiological investigations of COVID-19 clusters in France, the scientific literature, structured interviews and site visits were collected and summarised to investigate the main risk factors for SARS-CoV-2 infection in meat processing plants, including determinants within and outside the workplace.

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