Publications by authors named "N T Foss"
Article Synopsis
- Total knee arthroplasty (TKA) can lead to inflammation and significant pain, and this study explores how pain catastrophizing impacts acute postoperative pain and inflammatory markers (CRP) associated with TKA.
- The research involved 119 patients and included analyses of pain and CRP levels at 24 and 48 hours post-surgery to assess correlations.
- Findings indicate no significant relationship between preoperative or postoperative CRP levels and pain experienced or pain catastrophizing, suggesting that CRP may not be a reliable marker for assessing acute pain after TKA in patients treated with preoperative glucocorticoids.
Background: Patients undergoing emergency laparotomy present with a profound inflammatory response, which could be an independent pathophysiological component in prolonged recovery. The aim of this study was to investigate the effects of a single preoperative high dose of intravenous dexamethasone on the inflammatory response and recovery after emergency laparotomy.
Methods: In this double-blinded placebo-controlled trial, patients were prospectively stratified according to surgical pathology (intestinal obstruction and perforated viscus) and randomized to preoperative 1 mg/kg dexamethasone or placebo at a ratio of 1 : 1.
Article Synopsis
- This study evaluated factors that predict pain levels for patients after total knee arthroplasty, focusing on the days 2-7 post-surgery.
- It analyzed data from 227 patients to determine how preoperative and early postoperative factors, like pain levels and demographics, influence pain outcomes.
- Findings indicated that pain measured 24 hours after surgery is a strong predictor of pain during days 2-7, while preoperative pain only had a weak correlation.
Background: Delirium is an acute and fluctuating disturbance in attention, awareness, and cognition, commonly observed in hospital settings, particularly among older adults, critically ill and surgical patients. Delirium poses significant challenges in patient care, leading to increased morbidity, mortality, prolonged hospital stays, and functional decline.
Aim: The aim of this review is to map existing evidence on delirium diagnostic tools suitable for use in patients treated surgically due to hip fracture, to inform clinical practice and enhance patient care protocols in the postoperative setting.
Vasoconstriction with phenylephrine increases cardiac output in preload dependent patients.
J Clin Monit Comput
October 2024
General Anaesthesia (GA) is accompanied by a marked decrease in sympathetic outflow and thus loss of vasomotor control of cardiac preload. The use of vasoconstriction during GA has mainly focused on maintaining blood pressure. Phenylephrine (PE) is a pure α1-agonist without inotropic effects widely used to correct intraoperative hypotension.
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