Role of tumor necrosis factor-alpha -238 G>A promoter region polymorphism on recurrent miscarriage: An association study and meta-analysis.

Background: Recurrent miscarriage (RM) is defined as the loss of two or more consecutive pregnancies. A functional SNP, -238G>A in the promoter region of TNF-α, affects the gene transcription activity with implications on human pregnancy. Previous limited studies, linking the TNF-α -238 G>A to the risk of recurrent miscarriage have been inconclusive.

Impact of Interleukin-10 Promoter Region Polymorphisms on Recurrent Miscarriage: A Case-Control Approach.

Background: Recurrent miscarriage (RM), defined as two or more consecutive miscarriages prior to the 20 week of gestation is characterised by multifactorial aetiology. The prevalence of RM varies from 0.8% to 13.

Association Analysis of CYP11A1 Variants with Polycystic Ovary Syndrome: a Case-Control Study from North India.

The most common multifactorial endocrine disorder in females of reproductive age is polycystic ovary syndrome (PCOS), affecting about 5-10% of females worldwide and 9.3% of females in India. Androgen excess in PCOS is caused as a result of defects in steroidogenesis genes.

A Novel Approach to Recreate, Rehabilitate, and Restore the Facial Defect with a Partial Facial Mask - An Interesting Case Report.

Facial defects resulting from neoplasm, congenital malformation, or trauma can be restored with facial prosthesis using different materials and retention methods to achieve the life-like appearance and facilitate function. A facial prosthesis can re-establish esthetic form and anatomic contours for midfacial defects, often more effectively than by surgical reconstruction. For successful results, a lot of factors such as harmony, texture, color matching, and blending of tissue interface with the prosthesis are important.