Publications by authors named "N Storey"
Background: Multi-resistant Gram-negative bacteria (GNB) survive in hospital drains in traps that contain water and may ascend into the sink because of splashes, or biofilm growth.
Aim: To investigate whether the 'Tuba Drain' (TD) a long, bent, continually descending copper tube between the sink outlet and the trap prevents the ascent of bacteria.
Methods: After initial laboratory tests confirmed that the TD prevented bacteria in the U-bend from splashing upwards into the sink outlet, TDs were assessed in a randomized, blinded trial in a hospital outpatient department built in 2019.
Article Synopsis
- * The study compared two sequencing approaches: untargeted metagenomics using Illumina and Oxford Nanopore Technologies (ONT), and a targeted panel approach with Twist Bioscience's Comprehensive Viral Research Panel (CVRP).
- * Results showed that the CVRP significantly improved detection sensitivity for low viral loads, while ONT performed well at high viral loads but required longer runs at lower viral loads; ONT also had better specificity compared to Illumina.
Article Synopsis
- Metagenomics helps diagnose infections, but there hasn't been much comparison of methods for finding viruses across different labs.
- A study was done by the European Society for Clinical Virology to test twelve different lab methods using a special reference panel that simulates low amounts of viruses.
- The results showed that most methods could find common viruses, but some struggled with very low amounts, suggesting labs need to follow the same standards for better results.
Introduction: Neuropathic pain (NP) conditions involve lesions to the somatosensory nervous system leading to chronic and debilitating pain. Many patients suffering from NP utilize pharmacological treatments with various drugs that seek to reduce pathologic neuronal states. However, many of these drugs show poor efficacy as well as cause significant adverse effects.
View Article and Find Full Text PDFBackground: This analysis is the first systematic review and meta-analysis assessing occurrences of ICD in PD patients treated with oral DAs: ropinirole (ROP) and pramipexole (PRX). This study compares the two oral DAs to a transdermal patch, rotigotine (RTG).
Methods: We performed an extensive systematic search for eligible studies from PubMed, Embase, Cochrane Library, and Google Scholar.