Publications by authors named "N Steudel"
Article Synopsis
- Recent research indicates that maternal immunity and gut microbiota significantly influence obesity development in offspring, particularly through helminth infections in mice.
- Female mice infected with Heligomosomoides polygyrus (Hp) had offspring that gained less weight on a high-fat diet compared to those from uninfected mothers, suggesting protective effects from the maternal infection.
- The study highlights that the changes in gut microbiome composition and production of short-chain fatty acids (SCFAs) in Hp-infected mothers altered the metabolic outcomes in their offspring, emphasizing the importance of maternal health on obesity risk.
Purpose: The aims of this study on hepatic arterial Doppler sonography were to ascertain interobserver and interequipment variability, to investigate any potential artificial influence of the ultrasonic contrast agent on the Doppler measurements and to compare the results in healthy and cirrhotic subjects.
Methods: Doppler sonography of the left hepatic artery was performed in nine healthy and nine cirrhotic subjects by three independent observers using three different devices. Continuous infusion of the ultrasonic contrast agent SHU 508A and placebo were administered in a double blind fashion.
Background: Hypoxia may contribute to impairment of liver function and thus interfere with results of liver tests. In patients with cirrhosis, cytochrome P-450 mediated metabolism of substrates is facilitated in the presence of supplemental oxygen. It has not been studied how this relates to liver function and haemoglobin content.
View Article and Find Full Text PDFIn cirrhosis, hepatic arterial vasodilatation occurs in response to reduced portal venous blood flow. However, although the hepatic arterial flow reserve is high in patients with cirrhosis, its impact on hepatic function is unknown. This study investigated the effect of adenosine-induced hepatic arterial vasodilatation on different markers of liver function.
View Article and Find Full Text PDFBackground/aims: Doppler sonography has been used to assess hepatic arterial perfusion in a number of published reports. However, adequate validation studies are available for neither the transcutaneous nor the intravascular Doppler approach. The aim of this comparative study was to assess hepatic arterial perfusion with both methods.
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