Publications by authors named "N Sriram"
The transforming powder dressing (Altrazeal®, Uluru Inc, Addison, TX, USA) is simple to use, painless to apply and has a wear time of up to 30 days. This study aims to review the current literature to elucidate the impact of transforming powder dressing on healing, pain management and overall patient outcomes. We conducted a systematic review following Preferred Reporting Items of Systematic Reviews and Meta-Analyses guidelines.
View Article and Find Full Text PDFThe Clinical, Radiological and Genetic Spectrum of -Associated Neurodegeneration: An Experience From a Tertiary Center.
Tremor Other Hyperkinet Mov (N Y)
August 2024
Background: Despite being the second most common type of neurodegeneration with brain iron accumulation, there is limited literature on -associated neurodegeneration (PLAN) within the Asian ethnicity, particularly in the Indian context.
Methods: We conducted a retrospective observational study on patients with pathogenic/likely pathogenic variants based on exome sequencing.
Results: We identified 26 patients (22 families, 15 males) of genetically-confirmed PLAN with a median age of 22.
Space exploration has undergone a paradigm shift in recent years, with a growing emphasis on long-duration missions and human habitation on other celestial bodies. Private aerospace businesses are at the forefront of advancing the next iteration of spacecraft, encompassing a wide range of applications such as deep space exploration (e.g.
View Article and Find Full Text PDFArticle Synopsis
- - Painful diabetic neuropathy (PDN) is a common and challenging complication of diabetes, marked by nerve pain linked to changes in nerve cell activity and damage.
- - Research using single-cell RNA sequencing in a mouse model shows that the Mas-related G protein-coupled receptor d (Mrgprd) is overexpressed in certain pain-related nerve cells in PDN, and blocking its signaling alleviates pain symptoms.
- - The study suggests that targeting Mrgprd could lead to new and effective treatments for neuropathic pain in PDN, addressing a significant gap in current therapeutic options.
Article Synopsis
- This systematic review and individual patient data analysis aimed to summarize existing research on pineoblastoma, a rare type of brain tumor, and evaluate factors affecting overall survival.
- The study analyzed data from 44 studies and 298 patients, using methods like Kaplan-Meier analyses and Cox regression to identify significant predictors of mortality.
- Findings indicated that poorer prognostic factors included incomplete tumor resection, metastatic disease, and young age at diagnosis, but overall survival rates have improved significantly from 2012, rising from 32.8% to 56.1%.