Acute lymphoblastic leukemia occurring as a second malignancy: report of a case and review of literature.

Secondary leukemias occurring after the treatment of childhood malignancies are most often acute nonlymphoblastic leukemias. Only rarely do acute lymphoblastic leukemias (ALL) occur as second malignancies. An 18-year-old boy who developed ALL 4 years after Hodgkin's disease is described and the literature on secondary ALL is reviewed.