Relapse prevention: Using sound to reduce the probability of recidivism and suffering following detoxification.

The truth of the adage, "An ounce of prevention is worth a pound of cure", is exemplified by the opioid crisis now facing the world. While the best way to rid society of drug addiction is to prevent it from occurring in the first place, this is highly unlikely in the near future given the many ways that individuals can be first exposed to some potentially addicting substance. When an addiction is established, the first treatment for it is detoxification, but the insidious nature of addiction is its propensity to relapse.

MuGard, an oral mucoadhesive hydrogel, reduces the signs and symptoms of oral mucositis in patients with lichen planus: a double-blind, randomized, placebo-controlled pilot study.

Objective: To determine if MuGard, a mouthwash shown to reduce the severity of oral mucositis when started before initiating antineoplastic therapy for head and neck cancers, is effective when painful, oral lesions are present in patients with biopsy-proven erosive oral lichen planus.

Study Design: This was a double-blind, randomized, placebo-controlled pilot study at a college of dental medicine. Twenty patients with oral lichen planus were randomly assigned to receive either MuGard (n = 10) or saline-bicarbonate control (n = 10).