Endocr Metab Immune Disord Drug Targets
March 2021
Background: The importance of diet in health is widely accepted and recognized. Diet lipid profile is important to prevent chronic diseases and improve the quality of an individual's life.
Objective: The objective of this report is to analyze the effect of different sources of dietary lipids with standard and high concentration on growing rats.
Endocr Metab Immune Disord Drug Targets
October 2016
In the last decades, there have been many reports of HIV infection and abnormalities in lipid metabolism and cardiovascular disease (CVD). This study aims at describing the nutritional status of HIV-infected adults and its relation to lipid profile through traditional [total cholesterol (TC), HDL cholesterol (HDL), triglycerides (TG), non-HDL cholesterol and LDL cholesterol (LDL)] and other parameters [Apolipoprotein B (ApoB), fibrinogen, and high sensitive-C-reactive protein (hs-CRP)]. A cross-sectional descriptive study was performed.
View Article and Find Full Text PDFMalnutrition is a complex syndrome caused by an inadequate intake of energy, protein, minerals and vitamins which affects the immune system. Nutritional imbalances, present in children with energy-protein malnutrition and infections, make defining the specific effects of each of them on the thymus difficult. For this reason, it is necessary to design an experimental model in animals that could define a single variable.
View Article and Find Full Text PDFWe previously reported that combined fluoxetine administration at antidepressant doses renders additive antidepressant effects, whereas non-antidepressant doses potentiate the omega-3 fatty acid antidepressant effect. In the present study, we aimed to evaluate putative pharmacokinetic and brain omega-3 fatty acid-related aspects for fluoxetine potentiation of omega-3 fatty acid antidepressant effect in rats. Coadministration of omega-3 fatty acids with a non-antidepressant dose of fluoxetine (1 mg/kg day) failed to affect both brain fluoxetine concentration and norfluoxetine plasma concentration profile.
View Article and Find Full Text PDFEndocr Metab Immune Disord Drug Targets
August 2015
Background: A balanced diet is important to maintain an optimal health status and to prevent noncommunicable chronic diseases. The principal objective of this study was to analyze the effect of diets containing high fat levels from different sources, on serum and thymus lipid profile, in adult rats.
Methods: Experimental diets contained 50% kcal of fat, provided by butter (B) or sunflower oil (S); control diet (C) was isocaloric, with 15 kcal of fat per 100 total kcal, provided by soy oil.