Long-Term Outcome in a Phase II Study of Regional Hyperthermia Added to Preoperative Radiochemotherapy in Locally Advanced and Recurrent Rectal Adenocarcinomas.

Hyperthermia was added to standard preoperative chemoradiation for rectal adenocarcinomas in a phase II study. Patients with T3-4 N0-2 M0 rectal cancer or local recurrences were included. Radiation dose was 54 Gy combined with capecitabine 825 mg/m × 2 daily and once weekly oxaliplatin 55 mg/m.

Predictors for remission of major components of the metabolic syndrome after biliopancreatic diversion with duodenal switch (BPDDS).

Background: Metabolic surgery causes the remission of type 2 diabetes mellitus (T2DM), hypertension, and hyperlipidemia to varying degrees, depending on the patient characteristics and the surgical procedure. The aim of this study was to find predictors for the remission of T2DM and hypertension after biliopancreatic diversion with duodenal switch (BPDDS).

Methods: Eighty patients with T2DM were followed up for 2 years or more after BPDDS, and changes in body weight and metabolic status were noted.

The biliopancreatic diversion with a duodenal switch (BPDDS): how is it optimally performed?

Background: The biliopancreatic diversion with duodenal switch can be performed by different combinations of restriction and malabsorption. The aim of this study was to evaluate weight loss and potential side effects for two variants of the procedure.

Methods: All patients eligible for a 2-year follow-up (n = 182) was included in the study.

Anxiety and depression in association with morbid obesity: changes with improved physical health after duodenal switch.

Background: Patients with morbid obesity have an increased risk for anxiety and depression. The "duodenal switch" is perhaps the most effective obesity surgery procedure for inducing weight loss. However, to our knowledge, data on symptoms of anxiety and depression after the duodenal switch are lacking.

Health-related quality of life and paid work participation after duodenal switch.

Background: Morbid obesity can reduce the health-related quality of life (HRQL) and paid work participation, and the duodenal switch (DS) can induce large weight loss in patients suffering from this disease. However, data about HRQL combined with paid work participation after duodenal switch are lacking. The aim of this study was to provide longitudinal data of these issues.