Publications by authors named "N Sivapalan"

Article Synopsis
  • Glioblastomas are aggressive brain tumors that resist treatment and utilize neuron-tumor connections to promote their growth, with cholinergic neurons playing a key role in this invasion.
  • The study utilized rabies viruses for retrograde tracing to reveal how glioblastomas integrate into brain circuits, showing that radiotherapy can enhance neuron-tumor connectivity, complicating treatment efforts.
  • By disrupting neuron-tumor connections, researchers discovered a potential therapeutic approach that could halt glioblastoma progression, emphasizing the need to target these synapses for better treatment outcomes.
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Background: Complementary and alternative medicine (CAM)/natural products/herbs are frequently used for therapeutic purposes as a homemade remedy in Saudi Arabia. The use of CAMs is rising globally. However, special attention or precaution should be paid when using CAMs along with other drugs.

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Objective: To identify barriers to and facilitators of primary care provider (PCP) referral for bariatric surgery in patients with obesity.

Data Sources: MEDLINE, EMBASE, and PsycINFO databases were searched and reference lists of included articles were screened to identify additional relevant articles. Two reviewers independently reviewed citations and full-text articles, and appraised the quality of the included articles using the Critical Appraisal Skills Programme Tool Qualitative Checklist and the Appraisal Tool for Cross-Sectional Studies.

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Background: Primary care providers (PCPs) are typically the primary contact for patients with obesity seeking medical and surgical weight loss interventions; however, previous studies suggest that fewer than 7% of eligible adult patients are referred to publically funded medical and surgical weight loss interventions (MSWLI).

Methods: We performed an anonymous survey study between October 2017 and June 2018 to explore the knowledge, experiences, perceptions, and educational needs of PCPs in Southeastern Ontario in managing patients with class II and III obesity.

Results: Surveys were distributed to 591 PCPs (n = 538 family physicians; n = 53 nurse practitioners) identified as practicing in the Southeastern Ontario and 92 (15.

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Article Synopsis
  • Following bariatric surgery, lack of follow-up can lead to complications, less weight loss, and nutritional issues, making the patient experience in follow-up care crucial for optimizing results.
  • A study with 46 patients revealed that most valued regular contact with a dietician for support, but some expressed concerns about the usefulness of ongoing follow-up and preferred to rely on their family doctors.
  • To improve follow-up care and reduce dropout rates, the study suggests tailored, relationship-focused support that addresses the specific needs of bariatric patients while leveraging available local healthcare resources.
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