Publications by authors named "N Singer"
Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may occur after infection. How often people develop ME/CFS after SARS-CoV-2 infection is unknown.
Objective: To determine the incidence and prevalence of post-COVID-19 ME/CFS among adults enrolled in the Researching COVID to Enhance Recovery (RECOVER-Adult) study.
Importance: Classification of persons with long COVID (LC) or post-COVID-19 condition must encompass the complexity and heterogeneity of the condition. Iterative refinement of the classification index for research is needed to incorporate newly available data as the field rapidly evolves.
Objective: To update the 2023 research index for adults with LC using additional participant data from the Researching COVID to Enhance Recovery (RECOVER-Adult) study and an expanded symptom list based on input from patient communities.
Introduction: Mesenchymal stromal cells (MSCs) can modulate immune responses and suppress inflammation in autoimmune diseases. Although their safety has been established in clinical trials, the efficacy of MSCs is inconsistent due to variability in potency among different preparations and limited specificity in targeting mechanisms driving autoimmune diseases.
Methods: We utilized High-Dimensional Design of Experiments methodology to identify factor combinations that modulate gene expression by MSCs to mitigate inflammation.
Amygdala self-neuromodulation capacity as a window for process-related network recruitment.
Philos Trans R Soc Lond B Biol Sci
December 2024
Neurofeedback (NF) has emerged as a promising avenue for demonstrating process-related neuroplasticity, enabling self-regulation of brain function. NF targeting the amygdala has drawn attention to therapeutic potential in psychiatry, by potentially harnessing emotion-regulation processes. However, not all individuals respond equally to NF training, possibly owing to varying self-regulation abilities.
View Article and Find Full Text PDFArticle Synopsis
- Cardiac arrest severely impacts brain blood flow, with factors like bystander CPR, initial heart rhythm, and duration of arrest affecting patient outcomes; however, some neurological complications, such as PRES, are still not well understood.
- The case study discusses a patient with multiple health issues who experienced an out-of-hospital cardiac arrest but surprisingly achieved a strong neurological recovery, attributed to specialized management strategies.
- The findings underscore the need for multidisciplinary teams in the early diagnosis and management of complications like PRES in OHCA patients and highlight the necessity for further research to enhance understanding and treatment of these cases.