Publications by authors named "N Shanmugam Nagarajan"

Unlabelled: and like organisms (BALOs) predate on Gram-negative bacteria selectively, which holds promise as an alternate to combat against multidrug-resistant bacterial pathogens. In this study, two strains designated MPR17 and MPR18 were isolated from water samples by double-layer agar technique using as prey and investigated for their predatory potentials against six pathogenic Gram-negative, MDR and XDR bacteria. Both the BALOs preyed on all the tested bacteria including , , , , , and with different killing rates.

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Background: Staging of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMDs) is considered as the most important prognostic indicator, but salivary proteins such as interleukins (ILs) can serve as potential biomarkers. The aim of this study was to assess the presence of salivary IL-10 and IL-17 in OSCC and OPMD (oral submucous fibrosis and oral leukoplakia).

Materials And Methods: This was a hospital-based, in vivo, cross-sectional, comparative study.

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  • The study examines the relationship between skin oxylipins, which are bioactive lipids produced from fatty acids by skin microbes, and different microbial communities on the skin of children and adults.
  • Findings highlighted that Malassezia restricta, a type of skin fungus, has a positive impact on the production of a specific oxylipin (9,10-DiHOME) in adults, while showing a negative correlation with its precursor in children, indicating differences in skin chemistry across age groups.
  • The research suggests a complex communication system between skin microbes and host lipid metabolism that could have implications for skin health, emphasizing the need for further exploration of these interactions for potential therapeutic applications.
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  • - The study examines how different types of visual impairment (VI) in older adults relate to the likelihood of being hospitalized more than once, using data from a survey of Medicare recipients.
  • - Results show that older adults with any type of VI have a higher probability of hospitalization, especially those with near VI, who are about twice as likely to be repeatedly hospitalized compared to those without visual issues.
  • - The findings suggest that improving near vision may potentially reduce the chance of recurrent hospitalizations in seniors, indicating a need for further research on this topic.
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  • Poor vision (VI) may impact cognitive testing bias, which is critical to investigate, especially in regions with high VI prevalence and rising dementia concerns.
  • The study analyzed data from 3,784 participants aged 60 and above, examining the influence of VI on cognitive performance across various domains while adjusting for demographics and health factors.
  • Results indicate that although VI is linked to poorer cognitive scores, adjustments for potential bias show minimal impact on measurement differences, supporting that cognitive testing remains reliable despite VI presence.
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