Publications by authors named "N Sekarski"
Stress responses of infants and mothers to a still-face paradigm after traumatic childbirth.
Psychoneuroendocrinology
January 2025
Introduction: One-third of women experience childbirth as traumatic and some develop symptoms of childbirth-related posttraumatic stress symptoms (CB-PTSD symptoms). Whether CB-PTSD symptoms negatively impact on physiological and psychological stress responses in mothers and their offspring and whether they are associated with mother-infant synchrony is not clear. This study aimed to investigate stress responses of (1) mothers with CB-PTSS, (2) of their infant, and (3) the physiological mother-child-synchrony at six months postpartum.
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- Kawasaki disease, a rare inflammatory condition primarily affecting children under five, showed an 88% increase in incidence during the COVID-19 pandemic in Switzerland compared to the pre-pandemic period.
- The study analyzed data from 90 children, noting that 30% had been exposed to SARS-CoV-2, but other aspects like demographics and treatment remained similar.
- This research is the first extended European investigation into Kawasaki disease trends relating to the pandemic, highlighting significant shifts in its occurrence rates.
Fontan surgery is vital for infants born with a single-ventricle heart. This intervention establishes a new blood flow circuit bypassing the single ventricle, thereby the separating pulmonary and systemic circulation to preserve single ventricular function. However, it carries risks of hepatic complications, collectively termed Fontan-associated liver disease (FALD), characterized by progressive hepatic congestion and fibrosis potentially leading to an equivalent of cirrhosis.
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- The study investigated the effects of postoperative necrotizing enterocolitis (NEC) on neurodevelopmental outcomes in children who underwent cardiac surgery in their infancy.
- A total of 101 neonates with congenital heart disease (CHD) were examined, revealing that NEC resulted in longer stays in the intensive care unit and hospital compared to those without NEC.
- The findings indicated that children with NEC had significantly lower cognitive and motor scores on a developmental assessment tool at one year old, underscoring the negative impact of NEC on neurodevelopment.
Article Synopsis
- Sodium-glucose cotransporter type 2 inhibitors, specifically dapagliflozin and empagliflozin, have changed the game for treating adults with type 2 diabetes, heart failure, and chronic kidney disease, but their use in children is less established.* -
- A systematic review of clinical data involving 415 children showed that these medications were used in various conditions, including type 2 diabetes, kidney diseases, and other metabolic disorders, highlighting the potential for efficacy and safety.* -
- In two randomized trials focused on type 2 diabetes in adolescents, results indicated a notable reduction in glycosylated hemoglobin (HbA1c) levels, suggesting that dapagliflozin and empag