Publications by authors named "N Segnan"
Article Synopsis
- A significant portion of the disease burden in Italy is linked to lifestyle choices, specifically smoking and physical inactivity, prompting the need for a model to assess preventive interventions.
- The researchers developed a Markovian model to simulate health status and risk factors in the Italian population, providing insights on disease incidence and the effects of interventions over time.
- The model was validated with historical data and used to explore a hypothetical scenario of eradicating smoking and sedentary behavior, revealing potential long-term health benefits while highlighting the need for future model enhancements to integrate more data.
Importance: Randomized clinical screening trials have shown that sigmoidoscopy screening reduces colorectal cancer (CRC) incidence and mortality. Colonoscopy has largely replaced sigmoidoscopy for CRC screening, but long-term results from randomized trials on colonoscopy screening are still lacking.
Objective: To estimate the additional screening benefit of colonoscopy compared with sigmoidoscopy.
Background: Cervical cancer places a significant burden on low- and middle-income countries (LMICs). The EuroMed Cancer Network (EuMedCN) brings together cancer experts and stakeholders from the Mediterranean countries to promote sustainable cancer screening and support implementation of the WHO Global Strategy to Accelerate the Elimination of Cervical Cancer as a Public Health Problem.
Aim: To highlight the constructive role of EuMedCN in mitigating inequalities in access to cervical cancer prevention and screening across the Mediterranean LMICs.
Aim: The analyses here reported aim to compare the screening performance of digital tomosynthesis (DBT) versus mammography (DM).
Methods: MAITA is a consortium of four Italian trials, REtomo, Proteus, Impeto, and MAITA trial. The trials adopted a two-arm randomised design comparing DBT plus DM (REtomo and Proteus) or synthetic-2D (Impeto and MAITA trial) versus DM; multiple vendors were included.